The FDA’s Center for Veterinary Medicine has posted updated Cumulative Adverse Drug Experiences (ADE) Summaries Reports, containing data from 1987 through 11 April 2007.

More information about the ADE reports can be found here and here (the latter page describes limitations in the ADE reports). An FAQ on the ADE reports is here. The form for submitting an ADE is here.

Reports are arranged by active ingredient (generic drug names are used), species, and route of administration. Some drugs have hundreds or thousands of reports; others have only a handful. Each report includes a list of reported reactions. Unfortunately, reaction types don’t seem to be fully standardized, so one can find the same type of reaction listed several different ways. For example, the report on carprofen administered orally to cats lists eight reports of “K HI, BLD” and one report of “K HI, BLOOD.” Similarly, what is the difference between “HYPOTHERMIA” and “HYPOTHERMIA, BODY,” both of which are reported six times. Some of the reported reactions are puzzling: one cryptic reaction reported for carprofen is “BLD.”

Still, the ADE reports are a wonderful resource for veterinarians who might be wondering if the odd reaction they’re seeing to a drug has been reported by anyone else.